Clarkson is a home rule-class city in Grayson County, Kentucky, United States. The population was 875 at the 2010 census, up from 794 at the 2000 census. Once called "Grayson Springs Depot" after a nearby resort, the name was changed in 1882 to honor the resort's owner, Manoah Clarkson.Clarkson is known for its Honeyfest and is home to The Walter T. Kelley Company, a manufacturer of beekeeping equipment.